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KMID : 0378019840270100137
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New Medical Journal
1984 Volume.27 No. 10 p.137 ~ p.142
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A bacteriologic study of bile
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Abstract
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Billiary tract diseases are relatively common in Korea and the surgery of the biliaty tract diseases are dealt with many problems, because of frequent postoperative complications and resistant bacteria due to antibiotic abuse.
The purpose of this study is to provide a bacterial analysis of bile and guide for most appropriate management of biliary tract infection.
In this paper, 122 cases of abdominal surgery for biliary tract disease and 31 cases of abdominal surgery for non-biliary tract disease as a control group were examined with aerobic and anaerobic bacterial culture in the bile.
The results obtained were as follows;
1. The sex ratio in biliary tract disease was M : F=1 : 1.2 and peak age distribution was above fifth decade.
2. In 122 cases of biliary tract disease, 80 cases (65.6%) were positive culture in the bile. In 31 cases of non-biliary tract disease as a control group, 6 cases (19.4%) were positive culture in the bile. In 80 cases of positive culture patients, 4 cases (5%) were positive culture with anaerobic organism.
3. In order of frequency for positive culture in biliary tract disease were intrahepatic disease, common bile duct disease and gall bladder disease.
4. Most common bacteria were E. coli (35%) and Klebsiella pneumoniae (16.3%) and anaerobic bacteria was bacteroides fragilis. Mixed infections were 13 cases (16.3%).
5. In sensitivity tests of microrganism to the antibiotics, most bacteria were sensitive to general antibiotics. Especially, the most sensitive drugs were Pipemic acid and Gentamycin and most resistant antibiotic was Ampicillin.
6. By means of prophylactic antibiotic therapy, bile infection was not decreased.
7. Common bile duct dilatation, increased leucocytosis and increased level of liver function test (serum bilirubin, alkaline phosphatase, SGOT and SGPT) were related with bile infection.
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KEYWORD
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